Novel multifunctional cyclodextrin-based nanocarriers for drug encapsulation and delivery as a strategy to overcome current therapeutic drawbacks

 

Acronym: CYCLON
Title: Novel multifunctional cyclodextrin-based nanocarriers for drug encapsulation and delivery as a strategy to overcome current therapeutic drawbacks
Status: Active
Funding Organization: European Union

Marie Curie ITN # 237962

NCSR D

Role:

Coordinator
Leader in charge: Konstantina Yannakopoulou
Start Date: 1/10/2009
Duration: 48 months
Project Website: http://www.itn-cyclon.eu/
Summary The CYCLON project aims, through training of young researchers within a highly competent and multidisciplinary network, to develop a new generation of multifunctional drug nanocarriers based on a family of water soluble and biocompatible oligosaccharides, the cyclodextrins. The nanocarriers will be thoroughly studied and evaluated as delivery vehicles of anticancer drugs, especially photoactive ones. The fast and extensive development in nanoscience provides great opportunity to develop the next generation of pharmaceutical nanocarriers, i.e. drug delivery nanosystems, combining a variety of properties and aiming at combating many diseases. These nano-platforms can help in targeting specific locations, in controlling the release of therapeutic compounds, in enhancing the in vivo efficiency of many drugs, in increasing drug loading capacity, and in providing multifunctionalization of a therapy.

In this challenging field the network will offer to 9 Early stage Researchers (ESRs, PhD students) and 4 Experienced Researchers (ERs, post-docs) the opportunity to acquire a very wide scientific background based on both fundamental and applied research training and complementary skills, taking advantage of the differentiated scientific experience of the network groups.